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User blog comment:D. Cello/Assassinews 10/11 -- Desmond's Ancestry Revealed/@comment-78.149.154.111-20111013204129/@comment-1153722-20111013210815
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Caterina Sforza died in 1509, two years before Revelations starts... Also, she told Ezio that she didn't love him in the Brotherhood novel right before she left Rome, which broke Ezio's heart.
Just to prove how wrong you are even more...