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User blog comment:Master Sima Yi/Assassin's Creed III in 2011?/@comment-3538288-20110410184802/@comment-1153722-20110413090412
"because Ezio lived there and it contains the Vatican which are both (in my opinion) crucial to the story.." They're not crucial to the story at all. Ezio is just a part of the overall AC storyline, and the Vatican plays a very, very little role. If they were so important, they'd be heavily featured in the first Assassin's Creed and in Assassin's Creed: The Fall. And they aren't.