Hybrid

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The hybrids were a species of animals directly descended from those Isu who chose to interbreed with their human workforce. As a result of this interbreeding, hybrids were born without the artifical neurotransmitters that forced humanity's subservience to their Piece of Eden-weilding Isu overlords.

The only known hybrids, whose ability to disobey the commands of the Isu led to the outbreak of war in 75,010 BCE, were Adam and Eve.

Appearances

• Assassin's Creed II (first appearance)
• Assassin's Creed III: Liberation (mentioned only)