Adoration of the Magi

Leonardo da Vinci's Adoration of the Magi was an unfinished depiction of Mary and her child - Jesus Christ - in the presence of the Magi.
Painted between 1481, Leonardo's Adoration of the Magi was eventually purchased by the Ezio Auditore da Firenze and placed in the gallery at the Villa Auditore.[1] The painting was later lost during the Papal attack on Monteriggioni, led by the Templar Cesare Borgia.[2]
Six years after the attack on Monteriggioni, in 1506, Ezio Auditore - whilst looking for a now-kidnapped Leonardo - learned that the Adoration of the Magi held part of a map identifying the location of the Temple of Pythagoras, and that the painting was now on display in the Castel Sant'Angelo.[3]
With the help of his sister's courtesans, Ezio managed to mark and reclaim the painting.[3]