Mass Exodus
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Mass Exodus is a memory in Assassin's Creed: Brotherhood.
It is the first memory of the game, and took place right after the memories of Assassin's Creed II. After Minerva's speech, Ezio escaped the Vatican Vault along with his uncle Mario.

After leaving the Vault, Ezio and Mario are met by a group of Cardinals in gathered in the Sistine Chapel. They are angry with the Assassins for breaking into their holy place and causing trouble. Outside, in an enclosed courtyard more Cardinals were gathered and were chanting the following prayer:
- "For we wrestle not against flesh and blood, but against principalities, against powers, against the rulers of the darkness of this world, against spiritual wickedness in high places. Wherefore take unto you the armor of God, the shield of faith, wherewith ye shall be able to quench all the fiery darts of the wicked"
- ―The Cardinal's Prayer upon Ezio's escape[src]
Mario and Ezio then fought their way through the streets and use their freerunning skills to evade the Papal Guards and escape from the Vatican District. The two climbed on top of a tall tower overlooking the Tiber River, and attempted to destroy the Apple of Eden by dropping it in the Tiber. Before Ezio has the courage to drop the apple, Mario takes it from him. Then the two perform a Leap of Faith into the river.
Outcome
Ezio and Mario successfully escaped Rome and safely returned to Monteriggioni with the Apple.