Poison Blade
- "It's another blade design...for delivering poison!"
- ―Leonardo da Vinci
The Poison Blade is a Hidden Blade upgrade, essentially a hollow needle equipped with poison. Whoever Ezio inject with the poison will go berserk, swinging their weapon wildly and attacking all those in range before dying. Ezio can recharge this weapon by buying the poison from street doctors.
This weapon is one of the best the player will get in the game; This is because Ezio can kill someone without attracting much attention to yourself, and instead making people look at the person going berserk. If the people looking at the person berserking are the targets, Ezio can assassinate them quickly and silently, and they won't notice a thing. Additionally, the player can make someone go berserk as a distraction to draw guards away from the target and assassinate him. This is especially helpful during Assassination Contract missions, as most of the time the targets have at least 1 Guard with them.
Poison vials cost 175 florins each and Ezio can carry up to five vials, but poison pouch upgrades bought from a local Tailor raise the amount of vials Ezio can carry at once (by up to 15).