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Casa di Vespucci
The Casa di Vespucci was the residence of the Vespucci family in Florence and a major landmark.
Location
It was located in the San Giovanni district, and was featured notably in the 15th century. The residence was built in 1350 by an ancestor of Amerigo Vespucci, and was the first abode in Florence to have painted facades, which where later copied heavily in the Oltrarno district.
Assassin's Creed II
The residence was seen in the memory "Nightcap," where Ezio Auditore climbed into the house through the window to see Cristina Vespucci.
Assassin's Creed: Brotherhood
The Vespucci residence is also featured in the first two Cristina Memories of Assassin's Creed: Brotherhood which involve conflicts between Templar Vieri de' Pazzi and Assassin Ezio Auditore.