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Manhunt
Man Hunt is a multiplayer mode for Assassin's Creed: Brotherhood. Man Hunt encourages players to join in two teams of four, in which one team hunts the other. The sole goal for the hunted team is to survive the hunter's onslaught. After a half-time, the roles are reversed, and the hunted become the hunters. It is available at level 1.
References
http://www.youtube.com/watch?v=4qeGqO2lSuc - GamerSpawn talks to Games Designer Boris Maniora about the multiplayer aspect of Assassin's Creed Brotherhood,at the Paris Games Week 2010. So far, this is the only news of Man Hunt mode.