Cleopatra
Cleopatra VII Philopator (January 69 BC – August 12, 30 BC) was the last effective Pharaoh of the Ptolemaic dynasty of Egypt. At first, she shared power with her father and later her brothers, whom she married. She eventually gain sole control through her plotting and murders and started a liaison with Gaius Julius Caesar, who she had a child with: Caesarion.
After Julius Caesar's death, she aligned herself with Marcus Antonius, who she also had children with. Antonius eventually committed suicide after losing the Battle of Actium.
Soon after, Cleopatra was assassinated by Amunet, who used a snake (presumably an asp). However, the history books claimed she committed suicide using an asp. It is possible that she was in possession of a Piece of Eden, which would account for her assassination. Considering that Alexander the Great is said to have been in possesion of The Sword, and that his sarcophagus is believed to have been transfered first to Memphis and then to Alexandria following his death, it it quite possible Cleopatra came into possesion of it, perhaps also influencing Julius Caesar's interest in her and his so-called Alexandrian War.