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User blog comment:MeDeoPal/Assassin's Creed IV Story Ideas (Ye Be Warned Of Ye Spoilers)/@comment-95.49.161.166-20121110174150
They could go Fallout-style. Introduce a new character with little or nothing to do with Desmond, who in fact now becomes part of the backstory. Like they did with the Vault Dweller, the Chosen One, etc. in Fallout 1-3.