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Shop quest
Shop Quests were special quests given to Ezio Auditore by several types of shops around Rome during the Renaissance, and could be accessed at the stores located on Tiber Island. These quests required Ezio to gather rare, tradeable items, to obtain certain items from the store that could not be bought normally.
These rare items could be found in Treasure chests throughout Rome, and within Lairs of Romulus. They were available by tackling Borgia Messengers, by killing and looting Cento Occhi thieves or Hermeticists, or by sending Assassin apprentices on contract missions marked with stars.
Blacksmiths Quests
Exotica
- Items needed: 2x Shrunken Head, 3x Elephant Ivory, 3x Indian Diamond
- Reward: Unlocks the Seusenhofer Pauldrons and Seusenhofer Chest Guard
Blood Money
- Items needed: 7x Vlad the Impaler Coins
- Reward: Unlocks the Spada Lunga
Faith
- Items needed: 3x Terracotta Pot, 2x Totem, 2x Buddhist Prayer Beads
- Reward: Unlocks the Captain's Sword
Art Merchants Quests
Trendsetting
- Items needed: 2x Pomander, 3x Ambergris, 1x Papaver Silvaticum
- Reward: Unlocks the Vaticano Treasure Map
Tailors Quests
Pulling Threads
- Items needed: 8x Silk, 5x Cardinal's Purple Dye
- Reward: Unlocks the Large Quiver (Increases Crossbow bolt limit by 5)
Doctors Quests
Venomous
- Items needed: 5x Tomatoes, 3x Nutmeg, 1x Aconite
- Reward: Unlocks Fast Poison
Trivia
- After completing "Venomous," regular poison is no longer available for purchase.
- There are only two available Shrunken Heads in the game without the addition of The Da Vinci Disappearance DLC. This video shows the location of them.
- Aconite can only be found on Borgia Messengers without the addition of The Da Vinci Disappearance DLC. Otherwise, Aconite can be found on Hermeticists as well.